The Ghanaian was forced off the pitch early in the 21st minute following a seeming setback, his place taken by Yohan Cabaye.
"We’re more concerned about Jeffrey Schlupp coming off because he’s rolled his ankle and you always worry with those - that he’s damaged some ligaments - but we won’t know until he’s had the scan," Hodgson said.
"I’m hoping that him and Wilf [Wilfred Zaha] will recover.”
An injury will be a massive setback for the Ghanaian, who only made an injury return against Manchester United last week after an almost two-month absence.
He had been a key feature of Hodgson's set-up since the former England manager replaced Frank de Boer in September.
The German-born, who joined The Eagles from Leicester City in January last year, has made 22 Premier League appearances, involving 21 starts, so far this season.
Palace, meanwhile, won Saturday's game by a 2-0 score.