Zinedine Zidane's side will also be keen for revenge against the Catalan outfit, having suffered a shock 2-1 defeat against them in October.
Since then, Los Blancos have shown a marked improvement and they come into the game on the back of a three-game winning streak.
However, Girona have been defying expectations this season and they too will be emboldened by their own recent form, despite suffering a heavy defeat to Barcelona in February.
|Game||Real Madrid vs Girona|
|Date||Sunday March 18|
|Time||19:45 GMT / 15:45 ET|
|Stream (US only)||fubo TV (7-day free trial)|
TV Channel & Live Stream
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|beIN Sports||fubo TV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on TV on Sky Sports Football and it can be streamed live online using Sky Go.
|UK TV channel||Online stream|
|Sky Sports Football||Sky Go|
Squads & Team News
|Position||Real Madrid players|
|Defenders||Carvajal, Vallejo, Varane, Nacho, Marcelo, Theo|
|Midfielders||Kroos, Modric, Casemiro, Isco, Asensio, Kovacic|
|Forwards||Bale, Ronaldo, Benzema, Vazquez|
Madrid have been boosted by the return to full fitness of Luka Modric and Toni Kroos, but Sergio Ramos is unavailable as Zidane allows the defender to recover from a knock.
Potential Real Madrid XI: Navas; Carvajal, Varane, Nacho, Marcelo; Casemiro, Modric, Isco, Kroos; Ronaldo, Benzema.
|Goalkeepers||Iraizoz, Bounou, Lizak|
|Defenders||Espinosa, Mojica, Ramalho, Alcala, Juanpe, Muniesa, Planas, Maffeo, Villa, Diaby|
|Midfielders||Granell, Pons, Portu, Amagat, Aday, Luiz, Timor, A. Garcia, B. Garcia, Porro|
|Forwards||Stuani, Olunga, Lozano|
Girona boss Pablo Machin has a near-full squad to choose from with only Carles Planas expected to be unavailable.
Potential Girona XI: Bounou; Ramalho, Espinosa, Juanpe, Mojica, Maffeo; B. Garcia, Portu, Granell, Pons; Stuani.
Betting & Match Odds
Real Madrid are strong favourites to win the game according to dabblebet, who price them at 1/6. Girona are 14/1 to win and a draw is 15/2.
Real Madrid will have the chance to exorcise the memories of their 2-1 defeat to Girona back in October when they welcome the Catalan side to the Spanish capital on Sunday.
Despite going ahead through an Isco strike in that game, Los Blancos were undone by second-half goals from Cristhian Stuani and Portu, so they will be eager to set to record straight.
At the time Cristiano Ronaldo was struggling to find the net, but the 33-year-old has since rediscovered the kind of killer instinct that has been a defining characteristic of his time in Madrid.
With Ronaldo seemingly back to his former self and Zidane's men playing with confidence again Sunday's match is shaping up to be an entirely different affair to October's encounter.
However, they will have to remain cautious of Girona, who have been performing at a consistent level throughout the season and shown that they have what it takes to spring an upset.