The Catalan outfit are unbeaten in 28 league games and currently boast an eight-point lead over second-place Atletico Madrid ahead of the international break.
They've already defeated their visitors in the corresponding fixture in Bilbao back in October, so they will be confident in their ability to repeat that feat on Sunday.
|Game||Barcelona vs Athletic Club|
|Date||Sunday March 18|
|Time||15:15 GMT / 11:15 ET|
|Stream (US only)||fubo TV (7-day free trial)|
TV Channel & Live Stream
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|beIN Sports||fubo TV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on TV on Sky Sports Mix and it can also be streamed live online using Sky Go.
|UK TV channel||Online stream|
|Sky Sports Mix||Sky Go|
Squads & Team News
|Goalkeepers||Ter Stegen, Cillessen|
|Defenders||Pique, Alba, Digne, Vidal, Umtiti, Mina|
|Midfielders||Rakitic, Iniesta, Coutinho, Paulinho, Roberto, Gomes, Alena|
|Forwards||Messi, Dembele, Alcacer|
Valverde has named an 18-man squad for the match, which can be seen above. Notable absentees include Sergio Busquets, who suffered a fractured toe during the week against Chelsea, and Luis Suarez, who is suspended.
Potential Barcelona starting XI: Ter Stegen; Vidal, Pique, Umtiti, Alba; Rakitic, Paulinho, Coutinho; Iniesta, Messi, Dembele.
|Position||Athletic Club players|
|Goalkeepers||Kepa, Iago, Simon|
|Defenders||Saborit, I. Martinez, Y. Alvarez, Nunez, Lekue, Etxeita, De Marcos, Balenziaga, A. Lopez|
|Midfielders||San Jose, Benat, Iturraspe, Susaeta, Rico, Vesga, R. Garcia, Cordoba, Gil, Munoz, Nolaskoain|
|Forwards||Sola, Muniain, Williams, Merino, Aduriz|
Athletic will be without forward Iker Muniain, while midfielder Mikel Rico and defender Yeray Alvarez are considered doubts for the match.
Potential Athletic starting XI: Iago; Etxeita, De Marcos, Y. Alvarez, Lekue; Benat, Iturraspe, Rico, Cordoba, Williams; Aduriz.
Betting & Match Odds
Barcelona are favourites to win, with dabblebet offering odds of 2/13 on the Blaugrana. Athletic are deemed to be an 18/1 bet to win and a draw is more likely at 7/1.
While Barcelona are on course to win the title, Athletic are languishing in the bottom half and a chasm of 37 points separates the sides in La Liga
When they welcome Ziganda's side to Catalunya on Sunday it will be a particularly special occasion for their manager Valverde, who joined the Blaugrana from the Basque outfit last year
As such, he is all too aware of the threat that they pose and, despite their disappointing performance in the league, the 54-year-old was keen to emphasis their never-say-die attitude.
"It's a special game for me because of who we're playing," Valverde told reporters ahead of the game.
"They're a dangerous team because they've always been a spirited side especially when the chips are down.
"It's a team that comes together and they have the ability to overcome, so it's a tough opponent."
Barca will be without key players such as Busquets and Luis Suarez for the game, but with Lionel Messi in tremendous form they appear almost unassailable at the minute and Athletic's team spirit simply may not be enough.