| - Michael Agazzi | Goalkeeper | 7 Andrea Cossu | Midfielder | |
| - Marco Ruzittu | Goalkeeper | 8 Davide Biondini | Midfielder | |
| 22 Federico Marchetti | Goalkeeper | 10 Andrea Lazzari | Midfielder | |
| 24 Cristiano Lupatelli | Goalkeeper | 16 Mikhail Sivakov | Midfielder | |
| 39 Mauro Vigorito | Goalkeeper | 18 Andrea Parola | Midfielder | |
| 3 Lorenzo Ariaudo | Defender | 19 Mario Brkljaca | Midfielder | |
| 3 Luca Di Laura | Defender | 20 Simone Barone | Midfielder | |
| 6 Luis Diego Lopez Breijo | Defender | 25 Enrico Cotza | Midfielder | |
| 13 Davide Astori | Defender | 28 Radja Nainggolan | Midfielder | |
| 14 Francesco Pisano | Defender | - Daniele Caschili | Striker | |
| 15 Lino Marzoratti | Defender | 9 Nenê | Striker | |
| 21 Michele Canini | Defender | 23 Joaquin Larrivey | Striker | |
| 31 Alessandro Agostini | Defender | 27 Jeda | Striker | |
| - Rafael Eduardo Acosta | Midfielder | 29 Mattia Gallon | Striker | |
| 2 Ignazio Carta | Midfielder | 30 Daniele Ragatzu | Striker | |
| 4 Daniele Dessena | Midfielder | 32 Alessandro Matri | Striker | |
| 5 Daniele Conti | Midfielder | - Massimiliano Allegri | Manager/Coach |
| Player | Goals | Penalties | ||
|---|---|---|---|---|
 | A. Matri Cagliari | A | 11 | 2 |
 | Nenê Cagliari | A | 6 | 1 |
 | Jeda Cagliari | A | 5 | 2 |
 | J. Larrivey Cagliari | A | 3 | 0 |
 | A. Lazzari Cagliari | C | 3 | 0 |
| Player |
To |
From |
|
|---|---|---|---|
 | M. Agazzi Goalkeeper | Cagliari | Triestina |
 | L. Ariaudo Defender | Cagliari | Juventus |
 | D. Dessena Midfielder | Cagliari | Sampdoria |
 | C. Matheu Defender | Independiente | Cagliari |
 | M. Brkljaca Midfielder | Cagliari | Hajduk |
 | S. Barone Midfielder | Cagliari | Torino |
 | M. Mancosu Midfielder | Empoli | Cagliari |
| Cagliari - Bari | 2/14/10 |
| Cagliari - Parma | 2/21/10 |
| Udinese - Cagliari | 2/24/10 |
| Chievo - Cagliari | 2/28/10 |
| Cagliari - Catania | 3/7/10 |
| Genoa - Cagliari | 3/14/10 |
| Cagliari - Lazio | 3/21/10 |
| Atalanta - Cagliari | 3/24/10 |
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