Aguero is certainly adept at hitting the ground running after scoring six goals in seven Premier League opening matches, and looks like solid value to maintain that reputation with another goal at 10/11 (1.91) odds.
Strike partner Gabriel Jesus will also be determined to remind everyone of his quality after a disappointing World Cup with Brazil, and can be backed at 6/5 (2.20) to hit the net for the sixth league match in nine.
Leroy Sane may also feel he has a point to prove after not making it into Germany's World Cup squad, and looks a good value longer bet at 17/10 (2.70) considering he has scored in three of his previous four league meetings with this opposition.
However, it is unlikely to be all one-way traffic considering Unai Emery's team is hardly short of attacking talent, with Pierre-Emerick Aubameyang a particularly exciting prospect.
Aubameyang should be particularly effective if he continues to work well in partnership with Alexandre Lacazette, whose own killer instincts in front of goal also make him a tempting anytime bet at 13/8 (2.63).
Both strikers are sure to benefit from the creativity of Mesut Ozil, who is on offer at 16/5 (4.20) to begin moving on from an unpleasant summer with the German national team by getting on target against the champions.