The Parc des Princes coach seemed unhappy at the media playing the blame game with his captain, while hinting that PSG's transfer dealings are finished for the summer
The reigning French champions will be without their captain for several weeks following confirmation on Wednesday that the Brazilian centre-back's hamstring problem is a serious one.
Blanc's feathers were clearly ruffled as he spoke to press about Thiago Silva's injury and, though he was adamant that the defender was not rushed back too soon, he nonetheless opted to publicly shoulder the blame.
"For me, no, I do not think that he took to the pitch too soon after the World Cup," the former France international told reporters on Thursday.
"Much has been said about the injury and who is to blame for his injury. Fine, I'll take the blame. The fault lies at my feet if it must lie somewhere.
"If we could have done things differently, we would have. Last year something similar happened and nobody said anything."
Blanc also revealed that les Parisiens' top targets have been signed and cast doubt over whether there will be any new additions to Parc des Princes this summer.
"I have an interesting and talented team," the trainer continued. "As long as the transfer window is open, admittedly, anything is possible, bu the players that we wanted we have bought.
"The main objectives for our transfer window are complete. But we do not always get our own way in the transfer window. If the squad remains as it is, I'll be very happy.
"If a player wants to leave, a third player might be brought in."
PSG have so far just brought in defensive duo David Luiz and Serge Aurier, from Chelsea and Toulouse, respectively.