The Manchester United boss looks set to be on his way out of Old Trafford less than a season into a six-year deal at the club
The Scot was 1/4 on to be shown the Old Trafford exit door and become the latest top flight boss to lose his job before the market was shut down at approximately 15:00 CET on Monday afternoon.
That came following widespread reports that the club have lost patience with the 50-year-old following Sunday's 2-0 Premier League defeat to Everton at Goodison Park.
The result leaves United in seventh position in the league table and 23 points behind leaders Liverpool, having lifted the title last season in Sir Alex Ferguson's final campaign in charge.
Moyes was appointed on the recommendation of Ferguson last May and handed a six-year deal following an 11-year stay at Everton, but his time already looks to be up after a disastrous 11 months at Old Trafford.
Several high-profile candidates have already risen to the top of the betting markets to take over at the Theatre of Dreams, with Netherlands boss Louis van Gaal the current favourite at 4/1.
Borussia Dortmund boss Jurgen Klopp and Atletico Madrid coach Diego Simeone are two other names believed to be under consideration at 5/1 and 18/1 respectively.
Should Moyes depart before the end of the season then United stalwart Ryan Giggs could be made caretaker boss until a permanent appointment is made, but the 40-year-old is a favourite with punters to be handed the job permanently at 6/1.
Outsiders include former Red Devils assistant manager Carlos Queiroz, who is a 14/1 shot, while Ferguson is available at 20/1 to make a shock return to the dug-out.