||Arsenal are 16/5 with William Hill to beat Bayern|
Arsene Wenger's side host the reining European champions, who have lost just two games in all competitions this season, at the Emirates Stadium on Wednesday evening.
Arsenal were knocked out at the round-of-16 stage last term by Bayern and Mertesacker hopes his team-mates have learned from the manner of their exit from the competition.
"We have to go for two perfect games against them. We know we can beat them now, so maybe mentally we are in a better condition that last year," Mertesacker told reporters.
"We respected them too much in the first leg then, so it was too easy for them.
"Maybe we have learned something from those lessons and will do better this time.
"Now we have another chance - and an opportunity to beat the champions. We want to achieve something exceptional this season, so we have to beat the best.
"That is not only Manchester City and Chelsea. That is Bayern Munich in the Champions League."