The embattled Manchester United striker is chosen to lead the line by boss Roy Hodgson despite having made only one pre-season appearance as the Auld Enemy face off at Wembley
The Red Devils striker, who featured just once for David Moyes' side thoughout the pre-season, but not in Sunday's 2-0 Community Shield victory over Wigan, gets the nod up front for Roy Hodgson despite transfer turmoil at the club level.
City stalwart Joe Hart takes up his usual post between the sticks, whilst Gary Cahill and Phil Jagielka pair in central defence flanked by full backs Kyle Walker and Leighton Baines.
Midfielders Steven Gerrard, Jack Wilshere, and Tom Cleverley each figure into the first eleven on the day, whilst pacy pair Theo Walcott and Danny Welbeck will play wide of Rooney in attack to round out the Three Lions' starting line-up.
Key Norwich performer Robert Snodgrass figures in boss Gordon Strachan's Scotland side, who will be without the experienced trio of Darren Fletcher, Gary Caldwell, and Steven Fletcher at Wembley.
England: Hart, Walker, Cahill, Jagielka, Baines, Gerrard, Wilshere, Cleverley, Walcott, Rooney, Welbeck.
Scotland: McGregor; Hutton, Hanley, Martin, Whittaker, Brown, Borrison, Snodgrass, Maloney, Forrest; Miller