The France international, on loan from QPR for the season, will be unavailable for the Magpies' Premier League opener due to a muscle strain
Magbpies boss Alan Pardew confirmed on Sunday that the 26-year-old, who has arrived on loan from QPR, had picked up a strain that will keep him out of the trip to the Etihad on August 19.
"We look like we need a bit of improvement at the top of the pitch," Pardew told The Chronicle. "We have Remy in and unfortunately he's injured, so that's still an area we need to improve on.
"It's just a strain but it's an area that is stopping him from running at the moment. We need to get some work into him.
"There is no chance of him making Man City. Whether there is a chance of him playing against West Ham in the next game is something we will have to suck and see as we go along."
The France international was in good form for QPR last season, despite their relegation, as he netted six goals in 14 appearances after joining from Marseille in January.