The 25-year-old is an integral part of David Moyes' attack and has enjoyed his recent meetings against Sir Alex Ferguson's league leaders going into their upcoming clash
The 24-year-old was instrumental in the club's 1-0 win at Goodison Park right at the beginning of the season, nodding in the winner, while he also bagged a double against the same opposition during the 4-4 draw at Old Trafford last term, which had a large bearing on the eventual destination of the league title.
However, after picking up a slight hip injury while on international duty, Fellaini feels that in order for the club to maintain their top four push this term, they need to perform against the best of what the top flight has to offer.
"First I look forward for Belgium and after we will see [what happens] against Manchester United,” Fellaini told the club's official website.
"Every game against Manchester United is a good game.
"It’s a big challenge but everyone wants to play Champions League so it is important to keep going and win every game."
David Moyes' side currently sit just three points adrift of Tottenham in fifth place going into the game at Old Trafford and after Fellaini scored a dramatic late double to help his side to a 3-3 draw at home to Aston Villa last weekend, he praised the spirit within the camp as responsible for the comeback.
He added: "It’s difficult to win when you make a mistake but Everton have good spirit and try to win every game at home. It was a good point.
"Every game I try to give my maximum and to score goals. It’s not just me – the players and supporters help, everything is important."