The 21-year-old has featured just four times for the Blues this season, leading to suggestions that he might be set for an exit when the transfer window reopens.
But, despite admitting there had been some interest from other clubs, Di Matteo reiterated his desire to retain the Spaniard with John Obi Mikel set to partcipate in the Africa Cup of Nations in January.
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"Romeu is a very young talent with good prospects for the future. He has offers from other clubs and especially from Spain but I have had calls from Italy as well. But he will not leave."