It’s the first time either player has completed a game since recovering from long-term injuries. Sagna missed much of last season while Wilshere has not played a competitive match in 17 months.
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The England midfielder and the French full-back lined-up in an Arsenal side that also featured Andre Santos, Francis Coquelin, Andrey Arshavin, Marouane Chamakh and Emmanuel Frimpong.
Despite the presence of a number of first team squad members, Arsenal lost the friendly 2-0 against a Chelsea XI that fielded John Terry in the first half.
Sagna started in his usual right-back position before moving to centre-back in the second half, while Wilshere was fielded in an advanced midfield role.
The English midfielder was still tirelessly breaking forward in the dying moments of the game - news which will be encouraging for Arsenal fans and Wenger.