Di Matteo's attacking choice is often the talking point and tonight's game is no difference with the Italian going with the Spaniard who has recently found a rich vein of formRoberto Di Matteo continued with Fernando Torres upfront on the back of his weekend hat-trick and his goal against Barcelona, keeping Didier Drogba on the bench.
Ashley Cole has also been relegated to the bench presumably with one eye on Saturday's FA Cup final against Liverpool with Ryan Bertrand coming in at left-back.
Branislav has been moved into the middle of defence as well deputising in the absence of both Gary Cahill and David Luiz who are both out with respective injuries.
No real surpises for Newcastle with Alan Pardew sticking with the stars who have served him well so far this season, although the return of French duo Gabriel Obertan and Sylvain Marveux to the bench may make an impact as a sub.
Chelsea starting XI: Cech; Bosingwa, Ivanovic, Terry, Bertrand; Mikel, Meireles; Ramires, Malouda, Sturridge; Torres
Subs: Turnbull, Cole, Essien, Lampard, Mata, Kalou, Drogba
Newcastle starting XI: Krul; Perch, Williamson, Coloccini, Santon; Tiote, Gutierrez, Cabaye; Ben Arfa, Ba, Cisse
Subs: Elliot, Ferguson, R.Taylor, Gosling, Obertan, Marveauz, Shola Ameobi