Sergio Aguero and Carlos Tevez start up front once again for Manchester City as Roberto Mancini's men look to close the gap on rivals Manchester United to three points.
In all Mancini makes just one change to the side which destroyed Norwich 6-1 at Carrow Road last Saturday, with Yaya Toure replacing Nigel De Jong in midfield.
Knowing defeat will condemn his side to relegation, Wolves boss Terry Connor makes four changes to the side which earned a point away to Sunderland last weekend.
Dorus De Vries replaces the injured Wayne Hennessey in goal, while Ryan Jarvis, Sebastian Bassong and David Edwards all start.
Wolves Starting XI: De Vries; Foley, Bassong, Stearman, Ward; Kightly, Henry, Davis, Edwards, Jarvis; Fletcher.
Subs: Ikeme, R. Johnson, Berra, Zubar, Milijaš, Doyle, Ebanks-Blake.
Manchester City Starting XI: Hart; Zabaleta, Kompany, Lescott, Clichy; Barry, Yaya Toure, Nasri; Silva, Aguero, Tevez.
Subs: Pantilimon, Kolarov, Kolo Toure, A. Johnson, Milner, De Jong, Dzeko.