Liverpool start Andy Carroll, Luis Suarez and Steven Gerrard together for the first time as they face Brighton in the FA Cup.
Kenny Dalglish makes three changes to the Liverpool side which lost to Manchester United in the Premier League last weekend.
Carroll returns to the starting line up to partner Suarez up-front, Jamie Carragher replaces Daniel Agger alongside Martin Skrtel in defence, whilst Charlie Adam comes in for Jay Spearing.
Meanwhile, Brighton start with struggling striker Craig Mackail-Smith on the bench and are forced to leave out cup-tied pair Gonzalo Jara and Joe Mattock.
Liverpool: Reina; Johnson, Carragher, Skrtel, Enrique; Henderson, Gerrard, Adam, Downing; Suarez, Carroll.
Subs: Doni, Maxi, Coates, Kelly, Kuyt, Shelvey, Spearing.
Brighton: Brezovan; Calderon, Greer, Dunk, El Abd; Buckley, Navarri, Bridcutt, Lua Lua; Barnes, Vokes.
Subs: Ankergren, Noone, Mackail-Smith, Rodriguez, Harley, Vincelot, Agdestein.