The victory reduced the gap at the top to six points.
Zamalek hit Military Production 2-0 to turn the heat on Al Ahly at the top of the Egyptian Premier League.
This was the 10th win in 11 games for a club that was hovering around the relegation zone at the start of the season.
The White Knights are now just three points behind their bitter rivals at the top of the table, though they have played two games more.
Midfielder Hussein Yasser and central defender Mahmoud Fathallah, scored to secure victory for Zamalek.
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