Rafael Benitez rotates the squad for the FA Cup fifth-round tie against the Championship club, with the likes of Yossi Benayoun and youngster Nathan Ake afforded starts
The captain's inclusion is one of eight changes to the team which lost 2-0 to Manchester City on Sunday, with the likes of Fernando Torres, Oscar and Victor Moses all coming in.
Youngster Nathan Ake is afforded his first start for the club after making his debut as a 90th-minute substitute against Norwich in December.
For Middlesbrough, Tony Mowbray makes three changes to the side which lost 2-1 at home to Millwall on Saturday, with Mustapha Carayol, Faris Haroun and Scott McDonald coming in.
Loanee Josh McEachran is ineligable to face his parent club.
Middlesbrough: Steele; Bailey, Bikey, McManus, Friend; Carayol, Williams, Leadbitter, Haroun; McDonald, Main.
Subs: Leutwiler, Zemmama, Emnes, Ledesma, Hines, Miller, Smallwood.
Chelsea: Cech; Ferreira, Ivanovic, Terry, Bertrand; Ramires, Ake; Moses, Oscar, Benayoun; Torres.
Subs: Turnbull, Cole, David Luiz, Lampard, Hazard, Marin, Ba.