Having joined Hamburg from Bayer Leverkusen during the summer window, the goalkeeper has been in impressive form since the beginning of the campaign, while the Schalke midfielder has been handed a debut call-up after making a successful switch from Monchengladbach.
"I am delighted that Rene has found his old form after his long injury," Low told reporters. "He should now also get a chance to present himself on an international level."
Low, however, stressed that the decision to select Adler had nothing to do with the performance of the other two glovesmen, but rather the 27-year-old's stellar displays of late.
"This is a decision for Rene Adler and not against Marc-Andre ter Stegen and Ron-Robert Zieler, who of course will remain in focus," he explained.
Meanwhile, Bayern Munich defender Holger Badstuber and Real Madrid midfielder Sami Khedira will both miss out on the fixture due to injury.
| Name | Club |
| Goalkeepers: | |
| Rene Adler | Hamburg |
| Manuel Neuer | Bayern Munich |
| Defenders: | |
| Jerome Boateng | Bayern Munich |
| Benedikt Howedes | Schalke |
| Mats Hummels | Borussia Dortmund |
| Marcel Schmelzer | Borussia Dortmund |
| Philipp Lahm | Bayern Munich |
| Per Mertesacker | Arsenal |
| Heiko Westermann | Schalke |
| Midfielders | |
| Lars Bender | Bayer Leverkusen |
| Julian Draxler | Schalke |
| Mario Gotze | Borussia Dortmund |
| Ilkay Gundogan | Borussia Dortmund |
| Bastian Schweinsteiger | Bayern Munich |
| Thomas Muller | Bayern Munich |
| Toni Kroos | Bayern Munich |
| Roman Neustadter | Schalke |
| Marco Reus | Borussia Dortmund |
| Andre Schurrle | Bayer Leverkusen |
| Mesut Ozil | Real Madrid |
| Attackers: | |
| Lukas Podolski | Arsenal |
| Miroslav Klose | Lazio |