The Bayern Munich striker, who is chasing Gerd Muller's goalscoring record, will surpass the legendary Jurgen Klinsmann's haul of 108 caps tomorrow evening
According to reports from Sportinformationdienst, Klose will line-up as the lone striker from the start, with his team-mate and Bundesliga top scorer Mario Gomez entering the fray after the first-half.
The report also suggests that Christian Trasch will line-up in central midfield alongside Toni Kroos as Low is without injured trio Sami Khedira, Bastian Schweinsteiger and Sven Bender. Andre Schurrle will play down the right-hand side after his excellent form for Mainz.
However, Borussia Monchengladbach's in-form attacker Marco Reus is set to miss the game in Sinsheim. Reus, whose goal in the play-off against Bochum secured Bundesliga football for Gladbach, will have to wait to make his debut as he is suffering from a muscle strain.
There is better news for Low concerning Koln striker Lukas Podolski, who will operate on the left-hand side of Germany's midfield after shaking off an ankle problem, which forced him to miss yesterday's training session.