Scans revealed that the Dutchman had only sprained his ankle, meaning he could return to fitness in time for the crunch Eredivisie clash against table-toppers AZ
The 21-year-old sustained the knock against De Graafschap last Wednesday, but the severity of the injury remained unclear, and there were fears that the forward may have broken his ankle.
But a second MRI scan has confirmed that the Netherlands international had only suffered a sprain and could return to action in time for the clash against Eredivisie leaders AZ on April 11.
"Luuk de Jong had a new MRI scan on his ankle on Tuesday," a statement on Twente's official website read.
"The procedure revealed that the forward's ankle is sprained. De Jong will now follow an individual training programme."
Steve McClaren's side host Roda JC on Saturday as they look to close the gap on second-placed Ajax, who are three points ahead in the Eredivisie standings.