|ADO Den Haag
Groningen 4-1 Vitesse
The guests started the match the better side of the two and came close to opening the score via Ismail Aissati in the first half. Nevertheless, the gifted midfielder's shot bounced back off the crossbar. Groningen then took over the initiative and Swedish international Andreas Granqvist gifted the hosts the lead with a converted spot kick after the interval. Tim Matavz then somewhat fortunate managed to double Groningen's lead before Petter Andersson made it three with a curled shot in the top corner. Marcus Pedersen pegged one back for Vitesse with an excellent finish, but Tim Sparv restored Groningen's three-goal lead minutes later to put the match to bed.
Ajax 1-1 NEC
Both sides failed to impress in the opening 45 minutes, but Ajax showed improvement in the second half. The Godenzonen eventually broke the deadlock in the 76th minute via flamboyant forward Mido. However, the Nijmegen side weren't impressed too much and young defender Bram Nuytinck restored parity only two minutes later to help NEC to a deserved draw.
PSV 5-2 Heracles
The Eindhoven side struggled in the opening 30 minutes against Heracles and the away side deservedly picked up the lead in the 27th minute when Brazilian forward Everton found the net. PSV didn't waste any time to level the score though and Balazs Dzsudzsak scored the 1-1 hardly ten minutes later before Ola Toivonen gifted PSV the lead in the dying minutes of the first half. Nevertheless, again Everton restored parity after sloppy defending from Orlando Engelaar and Wilfred Bouma. Heracles defender Peter Reekers then received his marching orders after a reckless foul and PSV cruised to a comfortable win in the remainder of the game. Toivonen scored the 3-2 after 74 minutes of play before Ibrahim Afellay and Marcus Berg piled even more misery on the Almelo side.
Twente 2-0 De Graafschap
The reigning champions were never really troubled by De Graafcshap and deservedly picked up the lead in the eighth minute. The referee had no other choice but to award Twente a free kick after a foul on Luuk de Jong and Theo Janssen fired home from just outside the area to make it 1-0. The Superboeren did their utmost to level the score, but lacked the quality to restore parity and Janssen eventually decided the game with yet another superb free kick.
Willem II 1-1 Feyenoord
Feyenoord started the match the better side of the two and they opened the score after 37 minutes of play. Diego Biseswar reached Kelvin Leerdam inside the area with a good free kick and the defender tapped home from close range to break the deadlock. Luc Castaignos then came close to doubling Feyenoord's lead on two occasions, but the youngster failed to add his name to the score sheet. This proved costly in the dying minutes of the game when Ricky van Haaren beat his own shot stopper to help Willem II to an unexpected draw.
Utrecht 2-1 Heerenveen
Heerenveen came close to opening the score via Oussama Assaidi in the opening minutes of the game, but the tricky winger failed to beat Utrecht goalie Michel Vorm. The Friezen did break the deadlock though when Roy Beerens converted a spot kick halfway the first half. Utrecht immediately fought back and star player Dries Mertens levelled the score with a powerful left footed shot minutes after the opener. Both sides then got some chances to pick up the lead after the break and Jan Wuytens eventually helped the home side to the full three points with a good finish in the dying minutes of the match.
ADO Den Haag 0-2 AZ
AZ dominated play from the start and the 2008-09 Eredivisie champions deservedly opened the score after 40 minutes of play. Maarten Martens went to the ground inside the area and the referee had no other choice but to award AZ a spot kick. Rasmus Elm stepped up and duly slotted home from twelve yards. ADO were unable to do something back in the remainder of the match and Martens doubled AZ's lead after being set up by Brett Holman.