The 25-year-old insists Joachim Low's side side will not be playing for a point that would see both sides progress from World Cup Group G
The opening round of the group stage saw Germany defeat Portugal 4-0 and USA see off Ghana 2-1, but two draws on matchday two mean Portugal and Ghana trail the joint-leaders by three points.
Former Germany coach and attacker Jurgen Klinsmann is coaching the Americans, but Hummels insists there is no chance of Joachim Low's side playing for a point.
"We are not a team who plays for draws," the 25-year-old told a press conference. "We're definitely going to play to win and anything else would be totally unfair to all the other teams.
"However, if it's 1-1 in the 91st minute, I won't be dribbling past 4 players."
Germany required a Miroslav Klose header to rescue a point last time out after going 2-1 behind to Ghana - a match Hummels believes exposed some of his team's weaknesses.
"Against Ghana we showed weaknesses that we know are there and want to focus on them," he said. "Personally, I can be satisfied. But after two games relatively little has been done. I think we can improve in general."
The Dortmund stopper also refused to enter into the debate of whether captain Philipp Lahm should play at full-back or in midfield, asserting that is uninterested in exactly where they Bayern Munich man is deployed.
"We don’t discuss the whether we now have a favoured position for Philipp," Hummels continued.
"He does a good job in both positions and for me it is relatively unimportant whether he plays in defence or in midfield."