The midfielder thinks his team-mate will succeed where Brazil and Cameroon failed by getting on the scoresheet when the Group A opponents meet in Monday's decider
The forward missed the opening World Cup game when the Balkan side were beaten 3-1 by hosts Brazil but came back from suspension in style by scoring a double when they defeated Cameroon 4-0.
Modric, who was present in both matches in the heart of midfield, hopes to send Mexico's vocal fanbase home miserable by beating them in Monday's crucial final game, casting doubt on whether Ochoa is good enough to keep Mandzukic off the scoresheet.
"Mexico will have extraordinary support from their fans, but this is not an advantage for them and it's not an obstacle for us," the Real Madrid man told reporters on Sunday. "We will try to disappoint them.
"Mexico are a great team, they have shown a high level football, they have an aggressive style, but we are a better team and we have better individuals than Mexico.
"With all due respect to Ochoa, Mandzukic has scored against better goalkeepers than him."
If Mexico win or draw, they are guaranteed to go through to the last 16. Croatia will go out if they lose, while a draw would only see them go through if Cameroon, who are out, beat Brazil (who would immediately have a worse goal difference).
The two teams that qualify from Group A will face one of Netherlands or Chile, whose crunch clash to decide the group winner kicks off four hours beforehand.