The Uruguay defender believes he can give "useful information" to national team boss Oscar Tabarez, using his knowledge of his Juventus teammates to his side's advantage
La Celeste meet Cesare Prandelli's side in Natal on Tuesday, knowing that only one side can progress to the next round following Costa Rica's 1-0 win over the Azzurri on Friday.
Caceres joined the Bianconeri in January 2012 and revealed that he expects to be asked by the Uruguay boss about the club-mates he has that will make up part of Italy's side.
"I think coach Tabarez will ask me for information about Italy and Juventus, especially my club team-mates," the 27-year-old was quoted as saying in Gazzetta dello Sport.
"All tacticians know Andrea Pirlo, so I'll just reiterate to Tabarez how important it is to disturb him when he's in possession.
"Claudio Marchisio has some standard movements, so in this case my advice could be very useful. He knows how to burst between the lines and has a great shot from distance. I'll describe him in great detail.
"Giorgio Chiellini is a very good friend, while Andrea Barzagli and Leonardo Bonucci are very experienced.
"I don’t expect Italy to put 10 men behind the ball, as that is not their style. It suits us, as Luis Suarez and Edinson Cavani become deadly with a little space. We'll play on the counterattack."
After defeating England 2-1 on Thursday, Uruguay must now overcome Italy to progress to the last-16 and Caceres expressed his confidence in his side's ability to cause their opponents serious problems."Cavani with Suarez forms one of the best strike partnerships in the world," he continued.
"In the last game against England Suarez was incredible, though you could already tell from training that he was at 100 per cent.
"Uruguayans tend to give their best in difficult situations, as we already proved against England.
"Italy's defeat to Costa Rica surprised us all. It would've been better for us if the Azzurri had won. That way a draw was enough for both teams."