The former Barcelona and Chelsea forward is the Indomitable Lions all-time top scorer, having grabbed 56 goals in 115 appearances, and has won two African Cup of Nations trophies with his country.
Speaking ahead of Friday's Group A encounter, Enoh stressed that Cameroon will place a great deal of emphasis on their captain's performance and believes he will be instrumental in any World Cup success they enjoy.
"I think everybody knows Eto’o and his abilities," the Antalyaspor player told a press conference.
"He is our captain, our leader, he has a lot of experience and we hope he is in his best shape to lead us to victory.
"We know the Mexican team well, we worked a lot with the staff, but we are going to focus on our strengths and we are ready for tomorrow’s game."
Cameroon have had a long history in the World Cup, with this summer the seventh time they have entered the competition, and Enoh's hopes for a good run in the tournament are echoed by his teammate Nicolas N'Koulou.
"We are a united group, we are a family, we came here very motivated and we hope to compete well," the defender stressed.
"Everything is possible in a World Cup, we are all going to play. The most important thing for us is to win the three points, we'll play well and hope everything goes ok."