Germany are in one of the tournament's toughest groups alongside USA, Ghana and Portugal.
Low admitted that he has a good idea about which of his players will start the clash against the Seleccao in Salvador on June 16 but will first wait to see how his team acclimatise before confirming his selection.
"Of course I know roughly who will play. But the final decisions I will make after training sessions by who adapts well to Brazil,” Low told reporters.
"In Brazil, no one should expect that he can play all 90 minutes. Those who believe it are making a mistake.
"Under the conditions – the temperatures at 1pm local time – there will have to be a change in the game. There will be no team in this World Cup which will always use the same team."
Low will take charge for Germany’s fourth international tournament in a row as his side attempt to end their 18-year title drought in Brazil, with the 54-year-old having watched his side lose in the semi-finals at both the 2010 World Cup and Euro 2012.
And while he recently admitted that he thrives under the pressure that comes with coaching Germany, Low knows there is no magic formula to achieving success at a major tournament.
"In every tournament you know as a coach that in 90 or 120 minutes, it may be too late," he said.
"If a football nation like Brazil, Argentina, Spain, Italy or Germany were eliminated in the first round, then it is clear that all of the criticism would be focused on the coach."