La Roja's boss has stressed the importance of his side beating the Bleus on Tuesday night in Paris to avoid having to worry about qualifying for World Cup 2014 via the play-offs
La Roja conceded in the last 15 minutes of their World Cup qualifier against Finland on Friday, which ensured the game finished 1-1 and allowed les Bleus to forge a two-point lead at the top of Group I.
Del Bosque will want to avoid a third successive draw in qualification for the World Cup 2014 finals and a victory at the Stade de France would allow them to leapfrog Didier Deschamps' men.
The former Real Madrid boss told reporters on Sunday: "We will go to France to win. We have to play four more games [and] we must be optimistic.
"Tuesday is a very important match against France, but after that we will play three more games. We'll see how it goes."
It would be a major shock if the reigning world and European champions failed to qualify for the finals in Brazil next summer, though if they finish second behind France in Group I then they could still make it into the 32-team tournament via a play-off win.
Spain drew 1-1 with les Bleus in October last year at home, failing to replicate their 2-0 victory in the Euro 2012 quarter-finals against their neighbouring nation.