The 19-year-old Arsenal winger looked less effective in the second half on Friday, and the Three Lions boss feels he needs to maintain a more consistent level of performance
Hodgson's side host Ukraine on Tuesday in another World Cup 2014 qualifier, and the former West Brom boss intends to sit down with the Arsenal attacker and explain what he expects of him ahead of his first competitive match at Wembley.
The 19-year-old had excelled down the left flank throughout the opening period at the Zimbru Stadium, but his display fizzled out after the interval, something which concerned Hodgson, who told reporters: "I thought he'd been very good through that first half.
"But we'd made it clear to him we intended to take him off after 60 minutes, so I think he forgot to play in those first 15 minutes of the second half. That will be an interesting lesson for him as well."
Prior to the Moldova game, Oxlade-Chamberlain had admitted he was still learning his trade in the national and domestic set-up, after only breaking into the Arsenal first team at the beginning of 2012, and having only six caps to date for the Three Lions.
"I've always been a relaxed person, but when I get on the pitch I rely on my ability and trust in myself," Oxlade-Chamberlain told reporters.
"It's nice Roy has put such faith in me so far, but I don't consider myself an automatic regular starter yet."
He is likely to find himself in a team shorn of John Terry and Ashley Cole at Wembley; the latter is already ruled out, while a decision on Terry will be made imminently.