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Tottenham's draw against favourites Borussia Dortmund means they are now relative outsiders for this season's Europa League behind both Liverpool and Manchester United

After a difficult draw for the last 16, England’s Europa League contingent have seen their chances of glory take a significant hit.

Having been paired with tournament favourites Borussia Dortmund 7/2 (4.50), Tottenham Hotspur are now 12/1 (13.00) outsiders with William Hill to lift this trophy for the third time, 22 years since their previous triumph.

While Mauricio Pochettino’s men look assured of a top four spot in the Premier League, Liverpool and Manchester United will be taking this competition rather more seriously thanks to the reward of Champions League qualification for the winner.

With an enthralling tie in prospect between two historic rivals, both Jurgen Klopp’s and Louis van Gaal’s teams are now priced at 9/1 (10.00) to go all the way in this competition.

On the other hand, Sevilla’s chances of taking home this cup for the third consecutive season look as good as ever after a relatively kind draw against 40/1 (41.00) long shots Basel, with attractive odds of 6/1 (7.00) available on them completing an impressive hat trick.

Meanwhile, an evenly-matched tie between Bayer Leverkusen and Villarreal sees both teams priced at 12/1 (13.00) to claim the silverware.

Similarly, after being drawn together in an intriguing all-Spanish showdown, there is little to choose between Athletic Bilbao and Gary Neville’s Valencia in the betting, with odds of 16/1 (17.00) on offer on either side.

In contrast, Lazio 16/1 (17.00) will be heavy favourites when they take on Czech 66/1 (67.00) underdogs Sparta Prague, while Fenerbahce 25/1 (26.00) are expected to have the edge against 2011 finalists Braga 40/1 (41.00).

Having won the trophy for the only time in their history back in 2009, Shakhtar Donetsk are on offer at 16/1 (17.00) to find their way past Anderlecht 40/1 (41.00) en route to more glory this season.

Sevilla to win the Europa League at 6/1 (7.00) for a 1pt stake with William Hill

Al Hain-Cole is a Liverpool fan, experienced tipster and avid follower of European football. He specialises in accumulators and if you would like to read more from Al you can follow him on Twitter here.