Our Spanish expert Phil Kitromilides believes the European champions will be too strong for the Rojiblancos but still expects the side from Andalusia to get on the scoresheet
On the continent, however, a great deal of significance is placed upon this meeting of the winners of Europe's two major cup competitions.
Marke no mistake about it: both Real Madrid and Sevilla will be fully focused on lifting the trophy on offer in Cardiff, with Tuesday's game much more than just a pre-season run-out for both.
Paddy Power make the Champions League holders the clear favorites, with Madrid offered at 4/9 (1.44), while the Europa League victors, Sevilla, can be backed at 6/1 (7.00), with the draw offered at 7/2 (4.50).
In terms of their head-to-head record in La Liga last season, it was all-square between these two, with Madrid winning at the Santiago Bernabeu but Sevilla triumphing 2-1 at the Sanchez Pizjuan, although the aggregate score was clearly in Los Blancos' favour, given their 7-3 success in the Spanish capital.
The key point is, though, that this fixture tends to serve up plenty of action, with six of the last seven encounters seeing over 2.5 goals scored.
That might go some way to explaining the price of 4/9 (1.44) for at least three goals to be scored in Cardiff.
Slightly bigger odds can be found by backing both teams to score at 8/13 (1.62) - a selection that has also paid out in six of the sides' last seven meetings - yet for most punters that price is too small.
Instead, a more attractive option looks to be investing in Madrid to win and both teams to score, which is available
at the extremely healthy looking price of 13/8 (2.62).
This bet has proved the correct selection the last three times that the teams have met and makes sense: both teams have goals in them, but Madrid undoubtedly are stronger and should prevail in the end.
|Real Madrid to win and both teams to score at 13/8 (2.62) for a 2pt stake with Paddy Power|
Sign up with Paddy Power for up to £250 in free bets and back Phil's selection for this match
Phil Kitromilides is a sports journalist and TV presenter in Madrid