There were some emotional scenes at Fortaleza on Friday night as Brazil and Colombia battled it out in a breathless 90 minutes that will have some huge implications on the outright markets.
Plenty of punters signed in to back against the hosts but an early goal from Thiago Silva and a spectacular free kick from David Luiz ended Colombia's hopes of progression.
The last 20 minutes of that game could prove pivotal in the top goalscorer betting though, as James Rodriguez's penalty moved the Monaco man to six goals, two ahead of Lionel Messi, Thomas Muller and Neymar.
William Hill now have the 22-year-old at 10/11 (1.91) to scoop the prize which some punters may still be keen to get stuck into given the news that broke overnight regarding one of his closest rivals, Neymar.
Although Germany had progressed earlier in the day, giving Muller (11/2) at least two more games to try and better Rodriguez's tally, it was the injury to Brazil's poster boy that will grab the headlines.
The Barcelona forward, who had to be stretchered from the pitch in the closing stages of the match, was taken to hospital and fractured vertebrae looks to have ended his involvement in the competition.
Although Rodriguez is two strikes ahead, the impressive form of Lionel Messi could mean 5/2 (3.50) is the bet of choice for those who believe the Argentina frontman can lead his country to World Cup glory.
Alejandro Sabella's side face Belgium later today and with Messi potentially having three more matches to improve his tally if they progress, 5/2 (3.50) for a player of his quality looks a solid bet, especially as Argentina are much more likely to come up against teams who are willing to attack, rather than try to restrict them, much to the detriment of their own ability to play expansive football.
Dutch double Robin van Persie (10/1) and Arjen Robben (16/1) are both poised to challenge on three but perhaps have too much ground to make up, even with a clash against Costa Rica coming up.
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