Anyone opening a new Paddy Power account can benefit from a huge enhanced price of 5/1 (from 6/5) on Roy Hodgson's men getting three points on Thursday evening in Brazil
The Uruguayan defence looked particularly poor in the second half of that game, which should encourage England fans that three points is a realistic target for Thursday's game.
Paddy Power are offering anyone without an account the chance to back England at at 5/1 (enhanced from 6/5), which is sure to attract plenty of interest from those who believe the Three Lions can reproduce the kind of performance they showed against Italy.
Existing Paddy Power customers can benefit from another Money Back Special, which will see losing wagers on the first/last goalscorer, correct score and scorecast refunded if Uruguay win the game.
Daniel Sturridge was on target in that game and the Liverpool front man is the 5/1 (6.0) joint favourite to open the scoring together with Wayne Rooney, who was deployed in a wide role by Roy Hodgson against Italy.
Sturridge's club mate Luis Suarez was forced to sit out their defeat to Costa Rica but he is also a 5/1 (6.0) shot to break the deadlock with Edinson Cavani - who fired Uruguay into the lead from the penalty spot in their first game - available at 6/1 (7.0).
With Suarez back in the team the South Americans are without doubt a stronger unit than in their opening game but it remains to be seen whether the Premier League top scorer is actually able to play at anywhere close to the level he achieved last season at Anfield.
The 27-year-old underwent surgery just a few weeks ago and was deemed unfit to play against Costa Rica, even from the subsitutes' bench, which saw his side end the game two goals down to the 1/3 (1.33) pre-match favourites to finish bottom of Group D. Will his condition have improved sufficiently in five days to have a serious impact?
Although the England campaign didn't get off to a good start, the 5/1 (6.0) available to new Paddy Power customers is sure to prove a popular bet not only because it's almost three times the best price available elsewhere, but also because of Uruguay's defensive weakness, which Hodgson's men can exploit with a dynamic attacking line up including the likes of Daniel Sturridge, Raheem Sterling and Danny Welbeck.
Anyone without a Paddy Power account who wants to take advantage of these offers can sign up for one here.
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Jim Knight is Chief Betting Editor at Goal.com and has been tipping football games since he was old enough to place a bet. He is a Leicester City fan, writer and member of the We Are Going Up Podcast