Indeed, these will be the fourth and fifth meetings of the season between these two sides, with a potentially title deciding sixth on the final day of the campaign, and the previous encounters have been extremely tight affairs.
Three draws between Barca and Atleti so far in the current campaign show just how tough it is to split these two rivals, yet bet365 have the Catalans as the clear favourites for this evening's clash at Camp Nou, offering them at 8/15 (1.53) for the win.
Diego Simeone's men are available at a healthy looking 6/1 (7.00) while the draw can be backed at 10/3 (4.33).
Despite the disparity in odds, it is worth bearing in mind just how closely matched these sides have been so far this season, with two 0-0 draws and a 1-1 confirmation of the fact that we should not expect a high-scoring affair.
Under 2.5 goals is offered at 43/40 (2.07) which looks like an extremely solid option, yet for some slightly higher odds, the price of 11/8 (2.37) for a draw at half time looks supremely attractive.
It has paid out in three of their last four meetings, and has also proved to be the correct selection in other big games involving these sides in La Liga, namely last week's Clasico and last month's Madrid derby.
In a two-legged European knockout tie between two evenly-matched sides who know each other extremely well, a draw at half-time looks highly likely at a particularly attractive price of 11/8 (2.37).
|Draw at Half Time at 11/8 (2.37) for 2.5pts with bet365