Julen Lopetegui's team will have to improve on their previous showing and are up against a Uruguayan outfit which seems to be gathering some momentum.
Nevertheless la Rojita remain clear favourites for the win and are offered at 8/13 (1.62) with BetVictor. Uruguay meanwhile can be backed at 21/5 (5.20) with the draw priced at 3/1 (4.00).
The U20 World Cup is of course an excellent opportunity for spotting young talent, and in the aforementioned Jese Rodriguez, Spain boast one of the most exciting young players on the Iberian peninsula.
The Real Madrid Castilla forward has five goals in four matches and is continuing his record-breaking club form for his country.
Not to be outdone Uruguay themselves can count on the services of Nicolas Lopez with the 19-year-old Roma striker netting four times in the tournament and looking like a future star.
With two such talented front men on display, goals look likely, and backing both teams to score at 3/4 (1.75) is an excellent option.
Spain have scored in all four of their games so far, but have kept only one clean sheet, and that was achieved a little fortunately against Ghana. Meanwhile Uruguay have netted in their last three matches, meaning goals at both ends looks highly likely.
For a value bet, back a high-scoring game with over 3.5 goals available at a tempting 2/1 (3.00).
|Both teams to score at 3/4 (1.75) with Bet Victor
||Over 3.5 goals at 2/1 (3.33) with Bet Victor
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Phil Kitromilides is a sports journalist and TV presenter in Madrid