This is effectively the final roll of the dice for Roma with regards to qualifying for the Champions League. With Luis Enrique's side five points behind Lazio, who are currently occupying the final Champions League spot, anything other than a victory this evening would all but end the Giallorossi's hopes of returning to Europe's premier club competition.
An eleventh home win of the season for the capital-city side is priced at 6/4 (2.20) with Bet 365, while a victory for Napoli is on offer at 9/5 (2.80).
With Roma having won five of their last seven home games, and with Napoli having lost three of their last five matches, the price for a home win is certainly tempting.
Yet looking at the record of both sides makes backing goals in the game hard to resist and the price of 4/5 (1.80) for over 2.5 goals is well worth some investment.
Seven of Napoli's last nine matches have seen three goals or more, while Roma's last six games have gone over that line.
These two sides have the second joint highest goals per game average in the division at 2.97 goals a game, with Roma the second highest home scorers in Serie A, and Napoli the third most prolific side away from home. Bearing all this in mind, the price of 4/5 (1.80) for over 2.5 goals looks like exceptional value.
For those among you searching for bigger odds, then a small value bet on Roma to win both halves could make things interesting at 7/1 (8.00), a bet that has paid out in three of Roma's last five home wins.
UK readers can watch and bet on this match live with Bet365
|Over 2.5 goals 4/5 (1.80) with Bet365
Roma to win both halves 7/1 (8.00) with Bet365
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Phil Kitromilides is a sports broadcaster working on radio and TV in London and Madrid, you can also follow Phil on Twitter