The Italian and Spanish champions go head-to-head in an exciting duel in the Champions League at San Siro as they battle it out for a place in the semi-finals of the competition
Remarkably Wednesday's fixture will be the third meeting between AC Milan and Barcelona in this season's edition of Europe's elite club competition. Their two previous encounters in the group stage produced a total of nine goals, with Barcelona triumphing 3-2 at San Siro while AC Milan recorded an impressive 2-2 draw on their visit to Spain.
The Italians have home advantage in the first leg of their Champions League quarter-finals tie with the Catalans on Wednesday, and they will need to make the most of it ahead of a tough trip to Camp Nou in the reverse fixture.
||Ibrahimovic to score first
|The Swedish striker spent two years at Barcelona before his return to Italy and he has five goals in this season's Champions League. Four of those were openers.
||AC Milan to score two or more goals
|The Italians netted twice in both group matches against Barcelona earlier in the competition.
||Messi to score three or more
|The Argentine forward has the astonishing 12 goals to his name in this season's Champions League. In his last game in the competition he hit five goals against Bayer Leverkusen in an emphatic 7-1 win.
||Barcelona to win 2-0
|The Spanish club have triumphed on the road 2-0 in each of their last three away matches.
||At least two goals scored in the first half
|In both group games there were two goals in the first half. Furthermore, in the knockout stages there were also at least two goals before the break in three of the four games involving AC Milan and Barcelona.