They look destined to battle it out for the Premier League title but Manchester City and Manchester United also lead the chase for Europe's secondary club competition
Manchester United meantime were slightly less convincing in their win over Ajax, but nevertheless ensured progress to the next round, keeping alive the possibility of an all Manchester final in the competition.
The two rivals meeting in the final is just one of the many Manchester Europa League specials that Sportingbet are offering, and they price a derby in the final at 10/1 (11.00). Also available is the price of 11/10 (2.10) on either City or United winning the trophy and given the fact that they are the strongest two sides left in the tournament, it could hold some appeal.
Having dispatched Porto in the previous round, City face another trip to Portugal in the last 16 to face Sporting Lisbon, and Sportingbet offer 5/2 (3.50) on the Blues being eliminated by the Portuguese side.
The price is from the market on City's stage of elimination, with Roberto Mancini's side priced at 3/1 (4.00) to go out in the quarter finals, 4/1 (5.00) to be knocked out in the last four and 5/1 (6.00) on them finishing as runners up.
United are just behind City in the betting for overall winner, with the Blues on offer at 5/2 (3.50) to lift the trophy and the Reds priced at 100/30 (4.33). SportingBet also offer a market on United's stage of elimination with, amongst other prices, Sir Alex Ferguson's side offered at 9/2 (5.50) to finish as beaten finalists.
Sign up with Sportingbet now for a £50 risk free bet, topical specials and in play actionPhil Kitromilides is a professional sports broadcaster working on radio and TV in London and Madrid, you can also follow Phil on Twitter