Goal.com UK analyse the probable line-ups one by one...
With Jose Mourinho making his return to face his former club in London, Goal.com UK took an in-depth look at the Castrol Rankings and found the game could hinge on the lack of match time that Chelsea pair Ross Turnbull and Yuri Zhirkov have seen over the past 12 months.
Inter's primary advantage is that they have a settled XI, with most of their key players available. Chelsea, however, will have to rely on back-up goalkeeper Turnbull in place of regular No.1 Petr Cech, while Russian full-back Zhirkov will probably take the place of the injured Ashley Cole at left-back.
Position by position, Chelsea come out on top in the Castrol Rankings, winning eight of 11 head-to-heads. But the overall points tally lands in Inter's favour, primarily because of a 701 point 'victory' for Julio Cesar over Turnbull and another sizeable points advantage for Javier Zanetti compared to Zhirkov.
Chelsea outmuscle Inter in attack and midfield, but in defence - where Inter need to be strongest, as they would progress with a clean sheet - they have some potentially key advantages.
The Castrol Rankings produced the following results:
|Inter by 701pts
|Chelsea by 80pts
|Chelsea by 30pts
|Inter by 52pts
|Inter by 383pts
|Chelsea by 219pts
|Chelsea by 129pts
|Chelsea by 22pts
|Chelsea by 76pts
|Chelsea by 60pts
|Chelsea by 178pts
Overall head-to-head score: Chelsea 8 Inter 3
Overall points advantage: Inter by 142
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