The Dutchman is confident of upsetting the odds against his former side but says he is not harbouring any thoughts of revenge against the Spanish outfit
The Spanish giants are overwhelming favourites to reach the quarter-finals of the Champions League but the Dutch striker feels the Gelsenkirchen outfit, unbeaten in 2014, can defy the odds.
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"We will all need to have a good day," he told reporters at a press conference.
"If we are all at 100 per cent then we can make Madrid suffer."
Huntelaar went on to insist that he is not harbouring thoughts of revenge against Madrid, who sold him back in 2009 after just six months in La Liga.
"I want to be at my best in every game and tomorrow’s meeting with Real Madrid will be no different," he continued.
"We're still alive in the competition and now we're at the knockout stage. It's a huge game against a brilliant team. We're lucky that the first leg is at home.
"After that, we'll see what happens in Madrid. I really enjoyed my time there. The training complex is amazing, and the stadium too and the people at the club are great but now, my life is focused on Schalke."