The Catalunya coach explains how the Dutch outfit have the benefit of facing the Citizens early, and that the Champions League only gets more difficult in the winter months
Having defeated them already 3-1 earlier in the group stage, the 65-year-old is optimistic the Amsterdam giants can repeat their heroics from a fortnight ago and beat the English champions a second time.
"It's simple, you play to win," Cruyff told De Telegraaf. "In the event of a draw, you still risk losing and it will be very difficult regardless.
"I think it is an advantage that Ajax are playing Manchester City now. They must take the initiative [after their loss to Ajax]."
And according to Cruyff, the Eredivisie holders already have the momentum, saying: "There are many less chances [for Ajax] to make mistakes. Attacking teams are often set for trouble after November."