The Portuguese insisted that Los Blancos' most recent defeat is not a catastrophe but admitted that his side have been drawn alongside some difficult opponents
Goals from Robert Lewandowski condemned Los Blancos to a 2-1 defeat and saw them replaced by the Bundesliga champions at the top of Group D, however the 49-year-old was adamant that it is not a huge blow to their ambitions.
"We lost the game, but it is not dramatic. We are in a serious group, it's no joke. It is not satisfying, but we are second," Mourinho said in his post-match press conference.
"We now have six points. We have two games at home and it is within our reach to get the points needed to make the round of 16.
"I told my players that they were going to score their goals on the counterattack, and so it happened. I knew they would only have spaces in the transition game.
"There was a lot of pressure and it was difficult to get a balance. There were few opportunities and little creation."
Ajax's triumph over Manchester City leaves the group wide open and so the visit of BVB to the Santiago Bernabeu in a fortnight could prove potentially decisive for Madrid.