Los Merengues name the Ghana international at full-back in their team to face Jurgen Klopp's side, as they continue to deal with the absences of Fabio Coentrao and MarceloJose Mourinho has chosen to continue with Michael Essien at left-back for the Champions League match against Borussia Dortmund tonight, after the player impressed there against Celta Vigo at the weekend.
Elsewhere Real Madrid's starting XI is as expected, as they line up in a 4-2-3-1 formation with Sergio Ramos at right-back and Raphael Varane partnering Pepe in the centre of their defence.
Sami Khedira missed the match against Celta after sustaining a leg injury whilst on international duty, but he returns to the starting line-up this evening as part of a double pivot next to Xabi Alonso.
Mesut Ozil is preferred to Kaka in attacking midfield alongside Cristiano Ronaldo and Angel Di Maria, while the France international Karim Benzema gets the nod upfront ahead of Gonzalo Higuain.
Jurgen Klopp has included Mario Gotze and Marcel Schmelzer in his starting XI despite the two suffering from hamstring and foot injuries respectively during the course of the past week.
Robert Lewandowski starts upfront for the home side, and is supported by Gotze, Marco Reus and Kevin Grosskreutz who make up the attacking midfield three.
Borussia Dortmund (4-2-3-1): Weidenfeller; Piszczek, Subotic, Hummels, Schmelzer; Kehl, Bender; Götze, Reus, Grosskreutz; Lewandowski.
Subs: Langerak, Lowe, Felipe Santana, Leitner, Gundogan, Perisic, Schieber
Real Madrid (4-2-3-1): Casillas; Ramos, Varane, Pepe, Essien; Khedira, Xabi Alonso; Di Maria, Ozil, Ronaldo; Benzema
Subs: Adan, Carvalho, Albiol, Kaka, Modric, Jose Callejon, Higuain