Coach Pep Guardiola names a strong side for the Catalans' Champions League last 16 second-leg match at home to the German outfit. Barca lead 3-1 from the first leg
First-leg hero Alexis Sanchez picked up an injury at the weekend and misses out as Pedro and Cesc Fabregas start alongside Lionel Messi in attack.
In midfield, Xavi, Andres Iniesta and Sergio Busquets all start for the Catalans, while Carles Puyol, Eric Abidal and Thiago are all sidelined along with long-term injury victims David Villa, Ibrahim Afellay and Andreu Fontas.
Barca lead Bayer Leverkusen 3-1 from the first leg.
Barcelona (4-3-3): Valdes; Alves, Pique, Mascherano, Adriano; Xavi, Busquets, Iniesta; Pedro, Messi, Cesc
Subs: Pinto, Muniesa, Bartra, Keita, Sergi Roberto, Tello, Cuenca
Bayer Leverkusen (4-4-2): Leno; Schwaab, Reinartz, Toprak, Kadlec; Renato Augusto, Bender, Rolfes, Castro; Kiessling, Derdiyok
Subs: Giefer, Oczipka, Friedrich, Ortega, Zenga, Bellarabi, Schurrle