The Argentine is disappointed that the Azul will lose their most precious gem to Serie A in the coming year, but hopes that he will be the only player leaving
The 22-year-old will join the Serie A team in a €13.6 million move in January, after coming to attention in Universidad's stunning Copa Sudamericana campaign. He is still appearing for the U, however, and played in Sunday night's 2-1 victory over Universidad Catolica as Sampaoli's men look to cap their season with the Clausura crown.
Speaking on Monday, the Argentine coach recognised that Vargas' place in the team will be hard to fill, and said he hopes that the Chilean-record fee they will receive will mean that he is the only player who will leave in 2012.
"If Eduardo leaves, we do not want anyone else to go. Afterwards we as a coaching staff will see how we do this. Our obligation is to try and find a new Eduardo Vargas, it is a trainer's job," he told Triunfo.
Sampaoli added that Vargas and everyone else in the squad are committed to bringing another trophy to the club in 2011.
"It plays in our favour that those around Eduardo allow us not to think about what will happen in the future, and to think about today," he explained.
Universidad's next test will come this Wednesday, against Catolica in the second leg of their Clausura semi-final.