The 47-year-old had warm praise for the maestro, but wants Chile to secure three points at the Monumental despite the influence of the talented Barcelona striker
The South Americans meet in the Estadio Monumental for the first match of the 2014 World Cup qualifying campaign and both teams will be hoping for a positive start to the marathon three-year tournament.
Borghi is missing several key players, including Barcelona star Alexis Sanchez, but still insisted that he would not be going out to seek a draw.
"It is said a lot that it is good to salvage a point playing away. But in the  qualifiers we won quite a few games on the road which helped our qualification chances greatly," the trainer told reporters on Wednesday evening.
"This team has not lost the intention of always going out to look for three points, wherever we are. Chile have the conviction to achieve the victory."
Moving on, Borghi referred to Argentina No. 10 Messi and stated that it would be a devilish task to subdue the player widely recognised as the best in the world.
"Nobody has the recipe [to stop him]. In every game, he scores goals and plays well. You can put a personal marker on him, play a three-man, four-man defence and you still cannot stop him," the coach admitted.
Argentina and Chile will kick off on Friday at 2010 local time (0010 BST).