The Belgium international suffered a calf strain during the 2-0 victory over Paris Saint-Germain in the last round and has not featured since, missing the first leg in Spain and the top-of-the-table Premier League clash with Liverpool at the weekend.
|13/10||Chelsea are 13/10 with Bet365 to beat Atletico Madrid|
"Hazard is ready, it's my decision if he starts but he's ready," he told reporters.
Chelsea know a win will see them reach the Champions League final in Lisbon, having drawn the first leg at the Vicente Calderon 0-0, and Mourinho insists he "trusts" his players to get a result at Stamford Bridge.
"It's a knockout game, a game where maybe one goal is the difference. Everybody needs to be at the top level. During the 90 minutes the players are more important than the manager but I trust them and that helps me."
John Terry and Petr Cech also trained ahead of the crunch clash, and could feature at Stamford Bridge, with Mourinho confirming the former will start the second leg.
He said: "His partnership with (Gary) Cahill is fantastic, he deserves more than the Champions League has given him up until now. He starts tomorrow."
Love Champions League football? Then you'll love the great DVDs on offer at Goal's Official DVD Store - click here to take a look!