The prolific attacker continued his impressive scoring streak against Celta Vigo and has now scored versus 19 different sides in the Primera Division this term
The Argentina international beat Celta goalkeeper Javi Varas from close range in the 73rd minute after being set up by Cristian Tello to make it 2-1 for the Blaugrana, and take his season's league tally to 43.
Messi's goal was not enough for the full three points, though, as Borja Oubina restored parity in the closing stages of the encounter.
The 25-year-old's goal also saw him extend his scoring streak to an incredible 19 consecutive Primera Division matches.
Last season, Real Madrid attacker Cristiano Ronaldo became the first-ever player to score against every opponent in La Liga in one campaign since the extension of the top Spanish tier to 20 teams.