The Argentina international, who surpassed Cesar Rodriguez' record for the Catalans earlier this month, will receive special recognition ahead of the game at the weekend
The Argentina international broke the longstanding record of 232 strikes for the Blaugrana by scoring a hat-trick against Granada earlier this month.
The previous holder of the landmark, Cesar Rodriguez, played for the Spanish giants between 1942 and 1955, and no player had managed to surpass his achievement for more than 50 years.
Barcelona are set to honour Messi with a tribute before the match, but details are yet to be revealed.
According to Sport, there will be combined footage of both Rodriguez and the Argentine as a mark of respect to the widow and granddaughter of the former Barcelona player.
The game between the Catalans and Athletic Bilbao on Saturday kicks off at 22.00CET at Camp Nou.