The Blaugrana have managed to close to within eight points of league leaders Real Madrid after a weekend in which the Catalans cruised to a 2-0 win at Sevilla before Los Blancos conceded a last-gasp equaliser to Santi Cazorla in a 1-1 draw with Malaga at the Santiago Bernabeu.
There are those that believe that the title race is now very much back on, particularly those affiliated with the Camp Nou club, but Guardiola is adamant that Barca are already out of the running.
"It is difficult to see them losing more games," the former Spain international told reporters at a press conference on Monday evening.
"I still don't think we will win the league. Mathematically it is possible but I do not think we will make it.
"I said the same thing a few days ago: our objective isn't to be thinking about clawing those eight points back. I think that would be a mistake.
"It would be one thing if the gap was four or five points before they visit Camp Nou - that would be different; it would make that game a bit more decisive.
"But when you're trailing a team like Madrid by this amount of points, the best thing you can do is not think about staging a fightback.
"You can't start thinking, 'well, if we win this game and they lose this one ...'
"And besides, everyone is taking it for granted that we will beat Madrid at Camp Nou. It's a very tall order. It's not that simple. It won't be easy as some people think.
"So, no, I haven't changed the opinion that I had a few days ago. If I did a press conference every month I would change my opinion. But not now.
"I said what I said three days ago. It's impossible. Nothing has changed."
Still, Guardiola is desperate to see his side maintain their winning run against Granada on Tuesday night.
The former Blaugrana B team coach is calling for a 90-minute performance at Camp Nou after seeing his troops ease off a tad after moving two goals up inside 30 minutes at the Ramon Sanchez Pizjuan on Saturday night.
"The reality is that we have to compete well tomorrow [Tuesday]," Guardiola declared. "We have to play like we did in the first half hour against Sevilla."
Guardiola has led Barca to 13 titles since succeeding Frank Rijkaard as coach in the summer of 2008.
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